A similar situation is seen with organ transplant recipients who need immunosuppressant drugs to prevent organ rejection. A risk factor is something that may increase your risk for a disease. As you get older, your immune response will invariably begin to weaken. Dennis Sifris, MD, is an HIV specialist and Medical Director of LifeSense Disease Management. The two main types are Hodgkin lymphoma and non-Hodgkin lymphoma. Further research is needed to determine how these chemical toxins contribute to lymphoma and what risk they actually pose. Previous chemotherapy or radiation therapy. Having one or more of these risk factors does not mean you will get lymphoma. Philadelphia, Pennsylvania: Lippincott Williams & Wilkins; 2015. lymphocyte-depleted Hodgkin lymphoma (LHDL), bacterial, viral, and parasitic infections, mucosa-associated lymphoid tissue (MALT) lymphoma, Clinical, Molecular, and Environmental Risk Factors for Hodgkin Lymphoma, Does Gender Matter in Non-Hodgkin Lymphoma? Lymphocyte-Depleted Classical Hodgkin's Lymphoma: A Comprehensive Analysis From the German Hodgkin Study Group. The main subtypes are: 1. Lymphoma is not a single disease but a group of related blood cancers with numerous types and subtypes. Exposure to Agent Orange or other herbicides: Vietnam veterans and other people who have been exposed to Agent Orange or other herbicides are at increased risk of developing Hodgkin lymphoma. Stay informed and up to … Download our free mobile app — exclusively for physicians and physician offices — for direct access to a directory of Roswell Park physicians. Unlike autosomal dominant disorders in which there is a 50/50 chance of developing a disease if a gene is inherited, lymphoma doesn't have a clear pattern of inheritance. Somatic Mutation Theory: Why it's Wrong for Most Cancers, Immunoproliferative Small Intestinal Disease Associated with Overwhelming Polymicrobial Gastrointestinal Infection with Transformation to Diffuse Large B-cell Lymphoma, Common infection-related conditions and risk of lymphoid malignancies in older individuals, Epstein-Barr virus and the origin of Hodgkin lymphoma, Helicobacter pylori Strains and Gastric MALT Lymphoma, Hepatitis C virus and non-Hodgkin’s lymphomas: Meta-analysis of epidemiology data and therapy options, Primary effusion lymphoma: current perspective, Risk of non-Hodgkin lymphoma after radiotherapy for solid cancers, Dietary fat intake and risk of non-Hodgkin lymphoma in 2 large prospective cohorts, Risk of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) in a cohort of 3,546 women prospectively followed after receiving textured breast implants, NCCN Consensus Guidelines for the Diagnosis and Management of Breast Implant-Associated Large Cell Lymphoma, Familial predisposition and genetic risk factors for lymphoma, Exposures to multiple pesticides and the risk of Hodgkin lymphoma in Canadian men, Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL: Experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis, Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph Consortium, Organochlorines and risk of non-Hodgkin lymphoma, Body mass index and Hodgkin's lymphoma: UK population-based cohort study of 5.8 million individuals.