Hodgkin’s lymphoma, or HL, and non-Hodgkin’s lymphoma, or NHL, are the two main categories of lymphoma.The difference between the two was originally historical, but today HL and NHL are also known to differ in their microscopic appearances, typical course, and other characteristics. NHL is a term that's used for many different types of lymphoma that all share some of the same characteristics. Lymphoma is a form of cancer that affects the lymphocytes, a type of white blood cell that plays an important role in the immune system. Some forms are slow-growing, while others are fast-growing. With two similar-sounding names, Hodgkin lymphoma and non-Hodgkin lymphoma can easily be confused. Hodgkin’s lymphoma typically occurs between the ages of 15 and 40 or after 50. The diagnosis of Hodgkin's disease is confirmed by visualizing tissue samples using a microscope. If in examining the cells, the doctor detects the presence of a specific type of abnormal cell called a Reed-Sternberg cell, the lymphoma is classified as Hodgkin's. Both adult Hodgkin lymphoma and Non-Hodgkin lymphoma are types of cancer that develop in the lymphatic system, part of the body's immune system. Non-Hodgkin lymphoma (also known as non-Hodgkin’s lymphoma, NHL, or sometimes just lymphoma) is a cancer that starts in white blood cells called lymphocytes, which are part of the body’s immune system. The incidence of this cancer has actually been declining in recent years, in contrast to the increases in non-Hodgkin's lymphoma. Non-Hodgkin lymphoma (NHL) is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. Lymphoma is a type of cancer that begins in a subset of WBCs, called Lymphocytes (which are an integral part of the immune system). Lymphoma is a form of cancer that affects the lymphocytes, a type of white blood cell that plays an important role in the immune system. The main difference between Hodgkin's lymphoma and non-Hodgkin's lymphoma is in the specific lymphocyte each involves. Lymphoma is a cancer involving lymphocytes, a type of white blood cell. A doctor can tell the difference between Hodgkin's lymphoma and non-Hodgkin's lymphoma by examining the cancer cells under a microscope. Though the symptoms of Hodgkin and non-Hodgkin’s lymphoma can be difficult to detect, both symptoms include painless swelling of … In non-Hodgkin lymphoma… The primary difference between these two categories of lymphatic cancer is the type of lymphocyte that is affected. The difference between Hodgkin lymphoma and Non-Hodgkin lymphoma is that the cancer develops in different lymphocytes. Other symptoms may include bone pain, chest pain or itchiness. Hodgkin lymphoma is marked by the presence of Reed-Sternberg cells, which a physician can identify using a microscope. However, the primary difference between the two is in the specific lymphocyte each involves. Symptoms include enlarged lymph nodes, fever, night sweats, weight loss and tiredness. Hodgkin’s lymphoma is recognized as one of the most treatable cancers, with over 90% of patients surviving more than five years. Non-Hodgkin’s lymphoma does not contain Reed-Sternberg cells. There are Hodgkin’s Lymphoma and Non-Hodgkin’s Lymphoma; and these two lymphomas differ from each other in various ways. Are the symptoms of Hodgkin and non-Hodgkin’s lymphoma different? With two similar-sounding names, Hodgkin lymphoma and non-Hodgkin lymphoma can easily be confused.