Continue, 2. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. A dose of 15mg per kilogram has been given two or three times weekly in intermittent treatment regimens. If serum AST rises to more than three times normal, or there is any increase in bilirubin, treatment should be withdrawn. Start typing to retrieve search suggestions. When administered to nursing mother, breast-fed infants should be monitored for possible signs of isoniazid toxicity. any drug without checking with your doctor. Got a health query? Isoniazid dosage information (in more detail). A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. All patients should have baseline liver function tests performed and repeated at regular intervals during treatment. If you are allergic to this medicine (isoniazid tablets); any part of this medicine (isoniazid tablets); or any other drugs, foods, or substances. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. drug and while taking it. The usual daily dose for children aged three months and above is from 10 up to 15mg per kilogram body-weight daily in single or divided doses. Isoniazid 300mg Tablet is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). If you have high blood sugar (diabetes), you will need to watch your blood sugar closely. The dose of isoniazid for the treatment of tuberculosis is commonly 4 to 5mg per kilogram body-weight daily given by mouth in single or divided doses up to a maximum of 300mg daily. Do not share your drugs with others and do not take anyone else's drugs. Keep taking this medicine (isoniazid tablets) as you have been told by your doctor or other health care provider, even if you feel well. Isoniazid has no significant antibacterial action against any micro-organisms except the mycobacteria; against mycobacterium tuberculosis it is bacteriostatic in extremely low concentrations. Do not chew, crush or break it. When suggestions are available use up and down arrows to review and ENTER to select. Take this medicine in the dose and duration as advised by your doctor. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Please consult your doctor. what signs you had. I have cough problem from 25 days. There may be an increased risk of liver damage in patients receiving rifampicin and isoniazid but liver enzymes are raised only transiently. refer to chest specialist and do test for tuberculosis. Concomitant administration of isoniazid with itraconazole may result in significant decreases in itraconazole serum concentrations and therapeutic failure. It is considered that untreated tuberculosis represents a far greater hazard to a pregnant woman and her foetus than does treatment of the disease. 4.2 Posology and method of administration Official guidance should always be consulted when selecting the dose regimens to be used for adults and children (according to age and body weight), the duration of therapy and the total content of the combination treatment … The frequency of the reactions described below cannot be determined from the data available. These include the antiepileptics carbamazepine, primidone, and phenytoin, the benzodiazepines diazepam and triazolam, chlorzoxazone, and disulfiram. Forced diuresis may be tried and haemodialysis or peritoneal dialysis has been used. If left untreated it can spread through your body and may be fatal.